Cape Girardeau, MO

The small town of Cape Girardeau, Missouri, is situated on the Mississippi River, about 115 miles southeast of St. Louis, Missouri. This town is home to Southeast Missouri State University and the rich history surrounding its original settlement in the early 1700s and its role in the Civil War, occupied by Union soldiers and brief headquarters of General Ulysses S. Grant. This great town is the perfect place for residents and visitors to get their fill of education, history, commerce and medical care.

Cape Girardeau is located in the bootheel of Missouri with easy access to St. Louis via I-55. Our digital billboard in Cape Girardeau averages around 185,990 travelers per week.